By Nicholas Bakalar on July 3, 2018
Older women who took a probiotic supplement had less weakening of bones than women who didn’t take the supplements.
A probiotic supplement could be good for your bones, a new study suggests.
Researchers studied 90 women, 75 to 80 years old, all generally healthy but with low bone mineral density. They measured their bone density at the start of the study, and then randomly assigned them to a placebo or to two daily doses of freeze-dried Lactobacillus reuteri, an intestinal tract microbe that occurs naturally in many, but not all, people.
After one year, they measured the women’s bones again. The reduction in density in the shin bone was nearly half as large in women taking L. reuteri supplements as in those taking the placebo. Side effects, most commonly gastrointestinal symptoms, were similar in the treatment and placebo groups. The study is in the Journal of Internal Medicine.
The lead author, Dr. Anna G. Nilsson, said that why this happens is unclear. “Perhaps estrogens could be affected by probiotics,” she said, “and there is some discussion about calcium absorption, a change in the calcium regulating hormones.”
Dr. Nilsson, an associate professor at the University of Gothenburg in Sweden, said that it is not yet time to advise women to take probiotics. “This is the first study in humans,” she said. “We need confirmatory studies. And we’ve only studied one strain of L. reuteri, the type used in animal studies.”
Publish date: July 3rd 2018
Evidence continues to grow that screening for human papillomavirus infection bests a Pap test when it comes to catching early signs of cervical cancer.
In a large clinical trial of Canadian women, pap tests more often missed warning signs of abnormal cell growth in the cervix than did HPV tests, researchers report July 3 in JAMA. As a result, at the end of a four-year period, researchers found 5.5 new cases of severely abnormal, precancerous cervical cells per 1,000 women who got Pap tests, compared with 2.3 cases per 1,000 women who got HPV tests. Pap tests are the standard way to screen for cervical cancer.
“We should be moving away from screening with Pap tests toward screening with HPV tests,” says L. Stewart Massad, a gynecologic oncologist at Washington University School of Medicine in St. Louis, who wrote a commentary accompanying the study.
Previous research has found HPV testing leads to increased detection of abnormal cervical cells before they become cancerous compared with a Pap test. For instance, a 2009 study reported fewer cases of advanced cervical cancers and fewer deaths among women in India tested for HPV (SN: 4/25/09, p. 11). The study supported HPV testing in poorer countries, where cervical cancer screenings aren’t widespread. Worldwide, cervical cancer ranks fourth deadliest for women.
The new study suggests that HPV testing could also boost detection rates in countries that have well-established screening programs, such as the United States. Since the 1950s, the number of new U.S. cervical cancer cases and deaths has plummeted. The American Cancer Society estimates there will be 13,240 new cases, and 4,170 deaths, in 2018. The drop is primarily due to screening with the Pap test, in which cells are scraped from the cervix and examined for abnormal growth. But the test sometimes misses early signs of cancer.
An HPV test checks for the presence of a viral infection in cells swabbed from the cervix, similar to a Pap test. HPV, the most common sexually transmitted disease in the United States (SN Online: 4/28/17), causes nearly all cervical cancers. Following a positive result, doctors then examine the cervix for abnormal cells.
In the new study, roughly half of 16,000 Canadian women in an established screening program got the HPV test and the remainder a Pap test. After four years, all got both tests to check for missed cases. For the HPV-negative women, three more cases of abnormal cell growth were discovered after a Pap test. For women whose Pap test didn’t report abnormal cells, 25 additional cases were found after HPV testing.
“When [an] HPV [test] is negative, women are significantly less likely in four years to have anything abnormal,” says study coauthor Gina Ogilvie, a public health physician at BC Women’s Hospital and Health Centre in Vancouver.
A switch to a screening system that starts with an HPV test will require education for patients and doctors. “Some women in their 40s and beyond in decades-long stable relationships may be alarmed to be identified with a new sexually transmitted infection,” which may have been contracted years before, Massad says. It will be important to emphasize that “the goal of cervical screening is to identify and remove HPV-infected cervical tissue from women at high risk.”
ROCK STEADY FARM & FLOWERS
Start your summer off right! Take care of your health, eat fresh great tasting food AND support a local social justice farm doing great work in the community!
Rock Steady Farm & Flowers is a women and queer-owned cooperative farm, rooted in social justice, growing speciality cut flowers and sustainable vegetables in Millerton, NY.
Rock Steady now delivers weekly veggies and fruit to Elena-Maria Buruiana's OBGYN Office. As a women owned farm, we are super excited for a partnership with our long time friend and CSA member Elena! Her holistic outlook on health and wellness is aligned with our own mission as a farm.
SIGN UP BY MONDAY, JULY 9th!
WHAT IS A CSA?
Community Supported Agriculture (CSA) is one of the only ways to support local farmers directly. 100% of your dollar goes to our farm, located just two hours north of NYC. Your up-front commitment to buy local sustainably farmed veggies supports our farm and makes sure you get the very best of what we have to offer every week. More info on the CSA model can be found on our website.
Veggie Share - $25/week for 6-8 different crops.
Add-on's - Flowers, fruit, eggs, meat, cheese and yogurt!
When? - Starts every Wednesday, July 11th, 1-6pm. Ends in November.
LOW-INCOME PARTNER CSA SITE
All tax-deductible donations, as well as left-over shares incase members can not make it to pick-up, will go towards produce boxes for low-income patients at a nearby diabetes health clinic. Please consider making a donation when you sign-up.
SIGN UP TODAY!
2017 Rock Steady CSA Member Quotes:
"We have been members of four different CSAs over the last 25 years. Rock Steady is the best one yet - well organized, friendly, professional, and the tastiest veggies around! Winter is very long without our friends from Rock Steady!"
"I love the challenge of thinking of new ways to use the vegetables."
"These people believe in what they do, and believe in the community they do it for. The food and the people are both spectacular."
"Rock Steady Farm has the best CSA we've ever participated in. No question."
“I farm because I see it as radical action, a vehicle, to approach many of the injustices humanity and our natural world faces. Farming directly for my community, through a CSA, provides the opportunity for visibility and nourishment we all deserve.”
D. Rooney Farmer/Owner
We partner with other non-profits both upstate and in NYC to make sure ½ of our produce is going to low-income people. This is made possible through donations to their low income CSA fund, partnerships with pantries, gleaning organizations, EBT/SNAP access and sliding scale CSA. We also host 10 youth in the summer through a job training program!
Many thanks for supporting our farm!!
Farmer Maggie & The Rock Steady Farm Team
Publish date: May 29, 2018
By Andrew D. Bowser, Cardiology News
New perspective on sex steroids and CV risk
In postmenopausal women, a higher level of testosterone in comparison to estrogen may increase the cardiovascular disease risk later in life, results of a recent analysis suggest.
A higher ratio of testosterone to estradiol was associated with the development of cardiovascular disease, coronary heart disease, and heart failure in postmenopausal women, according to results from an analysis based on 2,834 postmenopausal women in MESA (Multi-Ethnic Study of Atherosclerosis).
In addition, total testosterone levels were associated with increased cardiovascular disease and coronary heart disease, while estradiol is associated with a reduced risk of coronary heart disease and heart failure with reduced ejection fraction, investigators reported in the Journal of the American College of Cardiology.
Without any interventional studies as guidance, it’s not clear what the “best strategy” would be to modify sex hormone levels and reduce cardiovascular disease risk, wrote investigator Di Zhao, PhD, of the department of epidemiology at Johns Hopkins University Bloomberg School of Public Health, Baltimore, and her study coauthors.
“Nonetheless, a more androgenic sex hormone profile may identify a woman at higher risk for cardiovascular disease who may benefit from other risk-reducing strategies,” Dr. Zhao and her colleagues wrote in their report.
The postmenopausal women included in this analysis all had baseline measurements of testosterone, estradiol, dehydroepiandrosterone, and sex hormone–binding globulin levels between 2000 and 2002, according to the report.
After more than 12 years of follow-up, investigators found that a higher total testosterone to estradiol ratio was independently associated with an increased risk of incident cardiovascular disease (hazard ratio, 1.19; 95% confidence interval, 1.02-1.40), coronary heart disease (HR, 1.45; 95% CI, 1.19-1.78), and heart failure (HR, 1.31; 95% CI, 1.01-1.70).
Posted by Dr.Buruiana on JANUARY 19, 2018
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By Ian Lacy
Publish date: DECEMBER 6, 2017 Ob.Gyn.News
A recent study published in the NEJM shows that women who use hormonal contraceptives including some types of IUD’s for more than a year have a 20%higher risk of breast cancer.
The absolute risk is still very low. It translates in one extra case of Brest cancer for every 7690 women using hormonal contraceptives for one year.
The risk is still less than a tenth of one percent, for a 40 year old it means a change from 1 in 69 to 1 in 57.
ACOG reports that the increase risk was equal to the increase from drinking alcohol.
This is an observational study and this new evidence does not change what we previously know about hormonal contraceptives and breast cancer risk.
The small risk has to be set against the benefits which includes prevention of unwanted pregnancies and “substantial reduction in the risk of ovarian , endometrial and colorectal cancer in life”.
NOV. 16, 2017 NY Times
Using accelerometers to precisely measure physical activity, researchers have found that even very light exercise, well below the generally recommended levels, reduces mortality in older women.
The scientists had 6,382 women ages 63 to 99 wear an accelerometer for seven consecutive days, waking and sleeping, except when bathing or swimming. Using this data, they were able to precisely quantify levels of activity without having to rely on self-reports, which can be unreliable.
The study, in the Journal of the American Geriatrics Society, followed the women’s health for an average of 3.1 years, during which time there were 450 deaths.
They found that for each 30 minute a day increase in moderate-to-vigorous physical activity, there was a 39 percent decrease in all-cause mortality. But they also found that 30 minutes of even very light activity — doing light household chores, walking slowly over short distances — was tied to a 12 percent reduction in mortality.
“The results apply to all women, all races, regardless of weight and even for women over 80,” said the senior author, Andrea Z. LaCroix, a professor of epidemiology at the University of California, San Diego. “You do not have to be a marathon runner to benefit from physical activity. We hope that physical activity guidelines will recognize light activity as an evidence-based way to lower the risk for death.”